Human chorionic gonadotropin (HCG) is a glycoprotein hormone secreted by the developing placenta beginning shortly after fertilization. At the time of the first missed menstrual period, HCG concentrations in serum and urine are about 100mIU/ml and double in concentration every 1.2 to 2 days. Peak levels of over 100,000 mIU/ml HCG are seen late in the first trimester of pregnancy. The early appearance of HCG in urine following conception has been made the marker of choice in the early detection of pregnancy.
Direct Pregnancy Latex Test
The Plasmatec direct pregnancy assay is based upon the latex agglutination reaction between latex particles coated with anti-HCG antibodies and HCG present in the test specimen. The presence of HCG in a urine specimen results in the formation of an agglutination matrix which is visually differentiated from the non-agglutinating negative control. The direct pregnancy latex test is calibrated to detect HCG levels at or greater than 200mIU/ml. The Plasmatec Pregnancy latex test kit comprises; latex test reagent, positive/ negative controls, pipette-stirrers and an agglutination slide.
One Step Pregnancy Assay
The Plasmatec lateral flow, one step pregnancy test is a chromatographic immunossay (CIA) for the rapid qualitative determination of HCG in urine. Based on the test’s high sensitivity, pregnancy can be determined as early as the first day of the missed menstrual period. The immunological specificity of the test virtually eliminates cross reactivity and interference of structurally related glycoproteins such as hFSH, hLH, and hTSH.